Here's mine from last night:
The quest is Gold Diggers from LotW in a LoR campaign so I equip Sun's Fury on Valyndra. My open groups are fire imps and arachyura. I'm using Tristayne's plot deck and have Wild Energy and Pariah. For the first couple rounds, the fire imps take pot shots at the heroes and move back, inflicting a few burn conditions and infection tokens. (I drew Contaminated in my starting hand) The heroes handle the fire imps and move up, healing as needed (they have an apothecary). Valyndra works on the miners, but rolls misses on 2 consecutive turns (I rolled an unusually high number of X's throughout the quest). When the first hero lands on the stream, there are two miners left. At this point, I'm not liking my chances. The heroes have been in complete control for the entirety of the quest, not a single hero has been knocked down so far and the 2 miners are at full health.
Then everything changed.
I start my turn by having Valyndra attack a miner. I get a great roll. 6 hearts and a surge. I use fire breath to hit both miners. The heroes rolled only 1 shield for each miner so they both go down and drop Jorem's Discovery. I have a master fire imp close by so he moves in a few spaces, picks it up and moves away a few more spaces. I then use Pariah to skip the activation of the arachyura to give the master fire imp carrying Jorem's Discovery another activation. He double moves for 10 MP. He is now 6 spaces away from the exit, Valyndra has almost full health, and 2 of the 4 heroes are a full turn away from getting into striking range of Valyndra. The quest is over, I have won. The heroes are not happy. Normally I offer up some constructive criticism at this point like "Your downfall was splitting up to explore the secret room" or "You should have blocked that hallway instead of chasing that monster" or something like that. I'm not really sure what to say so I say nothing. We'll probably wait a few extra days before attempting the next quest. They had that quest in the bag and everyone at the table knew it and then, in 1 overlord turn, the whole thing fell apart for them and they didn't even get a chance to react. Epic.