So my friend and I decided to try playing a game via MSN tonight. We both have our own copies of every expansion so we designated his as the "Master Board" and he would draw all Mythos cards and Encounters and tell me what happened and I'd echo it on my board.
With a random slection of Investigators, he ended up with Darrell and Trish and I had Zoey and Kate. The Ancient One was Chaugnar Fagn and the first gate opened on Devil's Reef. I won't bore you with the full details of the game, suffice to say it worked out fairly well. I rolled the dice and made the decisions for my Investigators but everything else was left for him to do. We reasoned that we couldn't both draw items for fear of duplicating one too many times, same for a Mythos card, etc. However, with hindsight, given how little I actually had to do, I think if we do it again then we'll have to come up with a way that I can draw cards after all. As it was, another of my friends was on MSN so I chatted with them while waiting for the "Master Board" to go through the motions. Possibly when he draw a Mythos card, I take it out of my deck and then on my turns just shuffle and draw. Same for items, etc. But with that one little niggle aside, it worked well. OK, we lost the game, too many gates opening on Investigators all the fecking time, but playing by MSN did kinda work. We hope to try again soon ...