Playing large (e.g. 5-6 player) games can be tough, especially with lots of expansions and numbers to track! I've played a few 6 player games using all expansions now and came up with ways to make things smooth. See if you like...
1. More dice!
a) Creature dice
I give each player his own die (the base game comes with 6: one for each player with extras if there are fewer players). Also, I give him a darker colored d6 that isn't included with the game. So for the whole game, each player hangs onto a light and dark colored d6.
When the player fights a creature, this allows him to roll both dice himself and use the darker one for the creature. Sure, it's fun to have your opponent roll, but if the night is long and your opponents aren't paying attention, it takes a while to get them to settle down and roll. With this method, you could have already finished your turn.
This also gives players an extra die if they regularly need it (e.g. Riding Horse).
b) "Value" dice
It's hard enough to remember all the cards that modify your stats, let alone ones that modify "values!" (Base number.) I've had several mistakes healing life or replenishing fate up to the printed number on my card, forgetting the value was actually higher.
If you have tiny d6's, you can place them on your character sheet to show an increased value. So, if you have a d6 with a "2" next to your fate, it reminds you the fate value is increased by 2. FFG sells tiny dice you can use: http://store.fantasyflightgames.com/productdetails.cfm?sku=FFS20
c) Strength and Craft dice
This is the big one. So many - so many - times, players spend minutes calculating and re-calculating their Strength and Craft. They add up their value (which can be wrong, as above), counters, and cards. And then do it again next combat, over and over.
We solved this by giving each player two d20's: one to show their total Strength and another their total Craft. Strength and Craft consists of the value, any counters , and any cards that modify the total. Any time one of these three numbers changes, the player turns the d20 to show the new total.
We don't include cards that modify conditionally - such as the Sword, which only works during battle. We only include cards like the Unicorn, which increase it permanently as long as you possess the card.
d) Downsides?
The value dice and the d20's are redundant, so you have to be diligent and honest to ensure they match reality. They work well, but not with someone who isn't focused and especially not with a cheater!
In the above photo, the Minstrel's two Destinies increase his Craft and fate values by 2, so the two tiny dice are placed there as reminders. He has 10 Craft: 6 value, 3 counters, and 1 modifier from the Unicorn. The d20 is set to show "10." The Sword doesn't show up on the d20 because it is conditional. He also holds onto a light and dark colored d6 throughout the game for all of his rolls.
2. Event Center
If you assign one person (i.e. yourself) to manage all of the upkeep that comes with expansions, the game will be faster!
With Blood Moon , I keep the Time Card as well as active Lunar Events next to me, and it reminds me to flip it and remember those Events are in effect.
With The Dragon (standard ending), I'm the "dragon keeper." I place all three Draconic Lord cards and their decks next to me, and before the game begins, I mix all the scales. I place the scales facedown in piles near the Draconic Lord cards. (Or put it into an opaque bowl). Something where you don't have to mix mix mix mix every turn. It adds up! I'm responsible for drawing a scale on each player's turn - and this saves tons of time!
You may wish to create an "Event Center." Pull up another chair if you don't have room at your table and place all the cards related to upkeep on that chair.
I have played a few 6 player games using all expansions, including The Dragon standard ending, and this Event Center made things flow. Each time the group was using The Dragon for the first time, no house rules - and they loved it! Great first impression. (You need to give them a good first impression to be sold on that expansion!)
This Event Center allows me to manage the Time Card, remember any Lunar Events in play, and lets me easily draw a dragon scale. The dragon scales are pre-mixed and placed facedown for easy drawing. The presence of the Reaper and Werewolf sheets reminds me to activate those figures.
Well, give it a try if you like these ideas!