Just read a wonderful battle report here where a team of Defender + Howlrunner + 3 TIE Fighters defeated a Han Solo build. I know that if anything, Han Solo builds are somewhat susceptible to the "death by a thousand cuts" approach of Swarms and Miniswarms.
What I'm wondering is how a Han Shoots First build should fight against a Swarm/Mini-Swarm. Should Han kill the Defender (or other big piece, usually a Firespray or Soontir) first? Or should Han and the X-Wings/Z-95s try to pick off the TIE Fighters?