Question that came up while I was playing, can you activate two house of knives' abilities on the same run? Pretty sure I can, but we were looking for the answer and can't find one.

Yes, the same card ability can't be used more than once but once per card is fine.

Thanks for the reply. Was just wondering if that makes it so that it's possible via those 2 scored HoK's to do 1 net damage each on the same run since the agenda says to use the ability only once per run.

Any limitation in self referential text only applies to that copy of the card.

Each House of Knives is restricted to once per run, but where there are multiple copies scored triggering one doesn't prevent the other from being triggered on the same run.

So yes, with 2 scored, you can deal 2 net damage to a runner on a single run by triggering each House of Knives.

Thanks for the quick replies guys. Resolved the question.